Clinical Efficacy of Therapeutic Drug Monitoring in Patients Receiving Vancomycin
نویسندگان
چکیده
منابع مشابه
Clinical efficacy of therapeutic drug monitoring in patients receiving vancomycin.
Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did not (non-TDM group, n=111). Creatinine clearance (CLcr) values decreased significantly after the ...
متن کاملTherapeutic drug monitoring of vancomycin.
Vancomycin, a glycopeptide antibiotic, was developed-and released in the 1950's for the treatment of aerobic gram-positive infections and has been widely used mainly in the treatment of methicillin-resistant Staphylococcus aureus infections. Early reports regarding the possibility of nephrotoxicity and ototoxicity led to concern about the use of vancomycin and the need to monitor serum concentr...
متن کاملA review of vancomycin therapeutic drug monitoring recommendations in Scotland.
NephSAP 2007; 6: 199–280. 6. Halperin ML, Kamel KS. Potassium. Lancet 1998; 352: 135–40. 7. Grimm PR, Sansom SC. BK channels in the kidney. Curr Opin Nephrol Hypertens 2007; 16: 430–6. 8. Oster JR, Singer I, Thatte L et al. The polyuria of solute diuresis. Arch Intern Med 1997; 157: 721–9. 9. Mittal VK, Pierce AK, Priestley JC. Use of probenecid in ticarcillin-induced hypokalemia. Clin Ther 198...
متن کاملGuidelines for Therapeutic Drug Monitoring of Vancomycin: A Systematic Review
BACKGROUND AND OBJECTIVE Despite the availability of clinical practice guidelines (CPGs) for therapeutic drug monitoring (TDM) of vancomycin, vancomycin serum concentrations still do not reach therapeutic concentrations in many patients. Thus, we sought to systematically review the quality and consistency of recommendations for an international cohort of CPGs regarding vancomycin TDM. METHODS...
متن کاملTherapeutic Drug Monitoring of Sirolimus,Correlation With Laboratory Parameters In Transplant Patients
Sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. Sirolimus must be used within a narrow therapeutic window. Due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. T...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2003
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.26.876